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pkrusche/README.md

Hi there!

I lead AI & data engineering in drug development by day. This is my personal account — personal projects, open-source history, and experiments.

Currently exploring agentic coding infrastructure:

  • project-sandbox — running coding agents in isolated containers and microVMs, with supervised or headless sessions, LLM-gateway credential isolation, and git-worktree / Jujutsu workspace integration
  • agentgateway-locally — keeping credentials out of the agent container, and using locally hosted models
  • jj-parallel-agents-skill — parallel agents on jj repos, plus an experiment in testing agent skills with evals
  • repljail — an MCP tool for network-isolated R sessions

Previously: genomics methods and benchmarking at Illumina — hap.py and Paragraph.

More on my blog

Pinned Loading

  1. Illumina/hap.py Illumina/hap.py Public

    Haplotype VCF comparison tools

    C++ 471 135

  2. Illumina/paragraph Illumina/paragraph Public

    Graph realignment tools for structural variants

    C++ 171 29

  3. Novartis/torchsurv Novartis/torchsurv Public

    Deep survival analysis made easy

    Python 215 16

  4. jj-parallel-agents-skill jj-parallel-agents-skill Public

    Jujutsu VCS Workspace skill for subagents.

    Shell

  5. project-sandbox project-sandbox Public

    Container/microVM sandbox for coding agents — supervised or headless sessions, credential and network isolation, git/jj workspace integration

    Python 1

  6. agentgateway-locally agentgateway-locally Public

    Setup script to run agentgateway locally

    Python